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Salicylic or mandelic: which acid for which breakout

Anti-Acne Serum on a bathroom shelf

Both acids exfoliate. The difference is where they work, and that decides which breakout each one is good for.

Salicylic acid: into the pore

Salicylic acid is a beta hydroxy acid (BHA). It is oil-soluble, so it can travel into oily pores and loosen the build-up that becomes blackheads and whiteheads. It also has a mild calming effect, which helps with small, inflamed spots.

Best for: blackheads, congested T-zones, oily skin, frequent small breakouts.

Mandelic acid: on the surface

Mandelic acid is an alpha hydroxy acid (AHA) with a larger molecule than glycolic acid. It moves into the skin slowly, which makes it gentler. It smooths rough texture and helps fade the marks breakouts leave behind.

Best for: sensitive or easily irritated skin, uneven texture, and post-acne marks on deeper skin tones.

Using both

Most acne-prone skin benefits from each, just not at full strength on the same night. A simple split works well: salicylic acid in the areas that clog, a few evenings a week, and mandelic acid on alternate evenings. Start low, add one product at a time, and wear sunscreen every morning.

If breakouts are deep, painful or leaving scars, see a dermatologist — over-the-counter acids are not enough on their own.